If you had only one question to ask Kubo-sensei, what would it be? Give me your question in a comment without any additional commentary.
You only have one question. That's one sentence, no use of multiple conjunctions ands ifs and buts and subclauses to complicate your question. I don't need to know why you want to ask your question. All I want is the question. Let the question speak for itself.
This would be my question: What significant changes did you mean for Orihime's character to undergo during the Arrancar arc?